Moderna vaccine efficacy is not contentious, it is one of the best available vaccines. The Moderna COVID-19 vaccine was the second COVID-19 vaccine to be authorized for emergency use in the United States.
It received authorization from the Food and Drug Administration (FDA) on December 18, 2020, about a week after Pfizer got approval. It’s an mRNA vaccine, which means it uses the same technology and mode of action as the Pfizer vaccine.
It works by giving your body instructions on how to create the spike protein unique to this virus. Your body then creates antibodies that will recognize and attack those proteins if they encounter the virus.
The Moderna vaccine requires two doses to be fully effective. It was found that up to 14 days after the first dose, the effectiveness was 50.8 percent. After that, it was about 92.1 percent. After the second dose, it takes about 2 weeks for your body to build full immunity. After that time period, the vaccine is approximately 94.1 percent effective.
You should get your second dose as close to the 4-week mark as possible. If need be, it’s OK to get it up to 6 weeks after your first injection. We don’t currently know the impact of delaying the second dose even longer.
Efficacy typically measures how well a vaccine works in a clinical trial, which is a controlled setting. Real-world effectiveness may be lower because of various reasons. At full immunization, the effectiveness of the mRNA vaccines (Pfizer and Moderna) at reducing SARS-CoV-2 infections, including asymptomatic infections, in the real world is 90 percent.
The trials are just a snapshot of the virus in the world at that given time. When the vaccine goes out into the general population, the prevalence of the virus might have changed, as well as any variants that may be circulating. This is another reason that real-world effectiveness might vary from clinical trial results.
None of the existing vaccines can completely prevent transmission, which is why it is still important to wash your hands regularly and follow distancing and mask guidelines based on the situation, space, and vaccination status of those around you.
If I don’t have a reaction, does that mean the vaccine isn’t working?
If you don’t have any side effects from the vaccine, you may see the reactions other people have and wonder if your vaccine was effective. The good news is, yes, your vaccine was still effective and you are protected. The side effects people experience are just reflective of each individual’s unique immune system, not of the vaccine itself.
Which vaccine should you get?
You should get the first COVID-19 vaccine that is available to you. Waiting for a specific brand is not advised. No vaccine is recommended over another.
What we know now
The Moderna COVID-19 vaccine is safe, effective, and comparable to the other COVID-19 vaccines on the market.
If you have any underlying health issues, talk with a medical professional about whether you should get the vaccine and any questions you might have about it.
Author: Gesture Chidhanguro